Mozzarella-Lover’s Mostaccioli Skillet with Ground Beef

If you’re a fan of Italian flavors and cheesy goodness, the Mozzarella-Lover’s Mostaccioli Skillet with Ground Beef is your go-to for an easy dinner option.

This meal has hearty ground beef and a generous amount of mozzarella cheese, making it the perfect comfort food.

To make this recipe you’ll need: mostaccioli pasta, ground beef, spaghetti sauce, condensed cheddar cheese soup, Italian seasoning, and mozzarella cheese.

It’s easy to make, and all you need are a few basic ingredients that come together in one skillet.

Ideal for anyone craving Italian food without having to leave the house. It’s also family friendly!

If you’d like some helpful Tips and Tricks, I have them below the recipe.

Vertical image of a mostaccioli pasta dish in a cast iron skillet, showing the pasta coated in a meaty tomato sauce and sprinkled with mozzarella cheese, presented on a rustic wooden table with dark background.

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Detailed image of Mozzarella-Lover's Mostaccioli Skillet with Ground Beef in a black cast iron skillet. The mostaccioli pasta is visible, mixed with ground beef and tomato sauce, topped with a layer of melted mozzarella and dusted with Parmesan cheese.

Don’t have a Cast Iron Skillet? This is the one we use, and would recommend:

If you need to change the amount of servings the recipe will make, click on the number of servings in the section under the “Print Recipe” bar, and move the slider up or down to change the number of servings you want.

Or to double or triple the recipe, click on the 2x or 3x next to “Ingredients”.

Vertical image of a mostaccioli pasta dish in a cast iron skillet, showing the pasta coated in a meaty tomato sauce and sprinkled with mozzarella cheese, presented on a rustic wooden table with dark background.

Mozzarella-Lover’s Mostaccioli Skillet with Ground Beef

Nesting Lane Indulge
Enjoy this Mozzarella-Lover’s Mostaccioli Skillet, with hearty ground beef and loads of cheese. Perfect quick, satisfying Italian dinner.
5 from 2 votes
Prep Time 10 minutes
Cook Time 1 hour
Total Time 1 hour 10 minutes
Course Main Course
Cuisine Italian
Servings 6



  • Cook the mostaccioli pasta as directed on the package for al dente. After cooking, rinse it with water and let it drain.
  • Heat a large iron skillet over medium-high heat. Cook the ground beef in the skillet, stirring until it is completely browned. Once browned, drain off any excess fat.
  • To the skillet with the beef, add the spaghetti sauce, cheddar cheese soup, ground black pepper, and dried Italian herb seasoning. Stir everything together until it is well mixed.
  • In a large pasta pot, combine the cooked pasta, the sauce mixture from the skillet, and 2 cups of shredded mozzarella cheese.
  • Place the mixed ingredients back into the iron skillet.
  • Sprinkle the remaining 1 cup of mozzarella cheese evenly over the top of the pasta mixture.
  • Bake the pasta in an oven preheated to 350°F for 40 minutes, or until everything is hot throughout.


Calories: 492kcalCarbohydrates: 43.4gProtein: 28.1gFat: 22.1gSaturated Fat: 10.5gCholesterol: 80.8mgSodium: 650.9mgFiber: 2.9gSugar: 5.5g
Tried this recipe? Let us know what you think!Mention @nestinglaneindulge or tag #nestinglaneindulge!

Tips and Tricks

Pre-Cook Pasta: Cook the mostaccioli pasta al dente, as it will continue to cook in the oven. This helps prevent the pasta from becoming too soft.

Brown the Beef Well: Make sure to brown the ground beef until it’s nicely caramelized. This adds a rich flavor to the dish.

Drain Fat: After browning the beef, drain the excess fat to keep the dish from becoming too greasy.

Season Well: Don’t skimp on the Italian seasoning. Adjust the amount to suit your taste and add a pinch of red pepper flakes if you like a little heat.

Layer the Cheese: For an extra cheesy experience, layer some of the mozzarella within the pasta, not just on top. This creates pockets of gooey cheese throughout the dish.

Use Quality Cheese: Opt for high-quality mozzarella for the best melt and flavor. Freshly grated cheese melts better than pre-shredded varieties, which often contain anti-caking agents.

Bake Until Bubbly: Bake the skillet until the top is bubbly and golden brown. If the cheese isn’t browning, you can broil it for a minute or two at the end of baking.

Let It Rest: Allow the skillet to rest for a few minutes after removing it from the oven. This makes it easier to serve as the cheese sets slightly.

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Pinterest-style image featuring 'Mostaccioli Skillet with Ground Beef' title above a skillet filled with baked mostaccioli pasta topped with ground beef and a generous layer of melted mozzarella cheese, set on a wooden table with red condiment containers in the background.

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